Inter
21.09.2025 21:45 (GMT+2)
Sassuolo
[1] - 1.30
Х - 5.80
[2] - 11.00
1$
1.30
1$
11.00

Inter — Sassuolo : Match Preview and Prediction for September 21,2025

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Inter vs Sassuolo: Serie A Clash on September 21, 2025

Match Preview: Inter vs Sassuolo

The Serie A Matchday 4 fixture between Inter and Sassuolo is scheduled for September 21 at the San Siro stadium in Milan. This comprehensive preview offers a detailed forecast, betting odds, and key statistics for the encounter.

Inter’s Current Form and Performance

Cristian Chivu’s squad recently suffered a 3-4 away defeat to Juventus in the previous round. Inter had led during the match but conceded two goals after the 80th minute, marking their second consecutive loss in Serie A. Despite these setbacks, the team has managed to score at least three goals in two matches this season. Milan currently leads the league in goals scored with 9, though their three points place them 11th in the standings.

Inter’s Home Performance Statistics

  • The club has won 8 of its last 11 home matches in Serie A.
  • At least three goals were scored in 6 of the team’s last 8 home league games.
  • Inter has conceded in 6 of their last 8 home Serie A fixtures.

Inter’s Probable Starting Lineup (3-5-2)*

Yan Sommer – Manuel Akanji, Francesco Acerbi, Alessandro Bastoni – Denzel Dumfries, Henrikh Mkhitaryan, Nicolo Barella, Hakan Çalhanoğlu, Carlos Augusto – Lautaro Martinez, Marcus Thuram.

Sassuolo’s Performance Overview

In their last match, Fabio Grosso’s side defeated Lazio 1-0 at home. This victory marked Sassuolo’s first win of the current Serie A season, ending a 5-match winless streak in the Italian top flight (1 draw, 4 losses). Additionally, it was only the second clean sheet for the team in their last 13 Serie A encounters. Sassuolo has accumulated three points and sits 14th in the league table.

Sassuolo’s Away Performance Statistics

  • The club has lost 10 of its last 12 away matches in Serie A.
  • Both teams scored in five of the team’s previous away league games.
  • Sassuolo conceded exactly 1 or 2 goals in 5 of their last 7 away Serie A matches.

Sassuolo’s Probable Starting Lineup (4-3-3)*

Arijanet Muric – Josh Doig, Tarik Muharemovic, Jay Idzes, Sebastian Walukiewicz – Nemanja Matic, Ismael Kone, Aster Vranckx – Armand Lauriente, Andrea Pinamonti, Domenico Berardi.

Match Referee Details

Livio Marinelli (Italy) Profile

Matches officiated – 17 (Serie A, 2024/25–2025/26);

Yellow cards shown (including second yellows) – 49;

Average yellow cards per match – 2.9;

Red cards shown – 3;

Average fouls per match – 23;

Penalties awarded – 24%.

Inter vs Sassuolo Match Prediction

Cristian Chivu’s team started the current championship season with a confident 5-0 victory over Torino but subsequently lost two consecutive matches, conceding a total of six goals. Furthermore, Inter’s home defense has not been particularly reliable lately: in their last eight home Serie A fixtures, the Milanese side managed only two clean sheets.

In the current championship, Sassuolo has already scored two goals in an away game against Cremonese, and previously, the club has been effective in attack: in their last five away encounters in the Italian top flight, the team found the net. Moreover, Sassuolo has scored in their last five head-to-head matches against Inter at the San Siro in Serie A, netting ten goals during this period.

Final Betting Tip

I anticipate at least one goal from the visiting team. Therefore, my prediction is: “Sassuolo Individual Total Over 0.5” with odds of 1.83 Bookmaker Logo

Prediction Author

Dmitry Shchurko

Disclaimer on Lineups

* The starting lineup for each team is based on their last match in this tournament.

Match Forecasts for Inter vs Sassuolo – September 21, 2025

Artem Egorov Profile Picture
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Artem Egorov
105 / 2 / 88 / ROI -1.6%

Artem Egorov’s Expert Forecast

The final match of Sunday’s Serie A program features Inter against Sassuolo. The Nerazzurri are having a faltering start to the season and desperately need three points, but Berardi and company will certainly not give them away without a fight.

Inter has lost their last two league matches, appearing significantly weaker than they were last season. In the game against Juventus, they led 3-2 with 15 minutes remaining but ultimately lost 3-4. It is evident that Cristian Chivu lacks coaching experience, which is reflected in their faltering finishes and dropped points.

Sassuolo has shown from the start that they have no intention of returning to Serie B. In the third round, they defeated strong Lazio (1-0), looking much more impressive (1.13 xG vs 0.76). Defender Muharemovic has been excellent, not only controlling the situation at their own goal but also providing assists.

Of course, Inter is considered the clear favorite, but it certainly won’t be easy for them. Earlier in the week, they had a tough away trip to Ajax (2-0), so many key players will need rest. Sassuolo has every chance to hold their own.

Expert’s Prediction

Sassuolo with a (+2) Handicap
Odds
Coefficient
1.58
 

History of confrontations

Last matches Inter vs Sassuolo

Inter Inter
Sassuolo Sassuolo

Other predictions

Sports betting from our team of predictors
Mark Thompson
Mark Thompson, a London-based journalist with 15 years of experience, is renowned for his deep knowledge of sports betting. His passion for football and analytical mind enable him to create accurate match predictions. Thompson regularly publishes articles revealing the intricacies of bookmaking. His ability to interpret statistics and assess team form is highly valued by readers and fellow professionals alike.
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